Is Leflunomide Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Leflunomide? Is Leflunomide safe for nursing mother and child? Does Leflunomide extracts into breast milk? Does Leflunomide has any long term or short term side effects on infants? Can Leflunomide influence milk supply or can Leflunomide decrease milk supply in lactating mothers?
Leflunomide lactation summary
- DrLact safety Score for Leflunomide is 7 out of 8 which is considered Dangerous as per our analyses.
- A safety Score of 7 indicates that usage of Leflunomide may cause toxic or severe side effects in breastfed baby.
- Our study of different scientific research indicates that Leflunomide may cause moderate to high side effects or may affect milk supply in lactating mother.
- Our suggestion is to use safer alternate options rather than using Leflunomide .
- Usage of Leflunomide is in contradiction to breastfeeding hence if it is must to use Leflunomide and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Leflunomide usage in lactation
We are working on a comment for this product.
Answer by DrLact: About Leflunomide usage in lactation
No information is available on the use of leflunomide during breastfeeding, so an alternate drug may be preferred, especially while nursing a newborn or preterm infant.[1][2]
Alternate Drugs
Rituximab(Low Risk)
Etanercept(Safe)
Auranofin(Low Risk)
Certolizumab Pegol(Safe)
Adalimumab(Safe)
Methotrexate(Low Risk)
Infliximab(Safe)
Leflunomide(Dangerous)
Sulfasalazine(Safe)
Tocilizumab(Low Risk)
Hydroxychloroquine(Safe)
Chloroquine(Safe)
Anakinra(Low Risk)
Abatacept(Low Risk)
Penicillamine(Low Risk)
Mercaptopurine(Safe)
Gemcitabine(Dangerous)
Fingolimod(Unsafe)
Sirolimus(Unsafe)
Cladribine(Dangerous)
Cyclosporine(Safe)
Dimethyl fumarate(Low Risk)
Azathioprine(Safe)
Pimecrolimus(Low Risk)
Methotrexate(Low Risk)
Everolimus(Unsafe)
Leflunomide(Dangerous)
Fluorouracil(Dangerous)
Tacrolimus(Safe)
Alemtuzumab(Low Risk)