Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-Q42T66VG0C? Is UNII-Q42T66VG0C safe for nursing mother and child? Does UNII-Q42T66VG0C extracts into breast milk? Does UNII-Q42T66VG0C has any long term or short term side effects on infants? Can UNII-Q42T66VG0C influence milk supply or can UNII-Q42T66VG0C decrease milk supply in lactating mothers?

UNII-Q42T66VG0C lactation summary

UNII-Q42T66VG0C is safe in breastfeeding
  • DrLact safety Score for UNII-Q42T66VG0C is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of UNII-Q42T66VG0C is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that UNII-Q42T66VG0C does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of UNII-Q42T66VG0C safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About UNII-Q42T66VG0C usage in lactation

UNII-Q42T66VG0C is excreted into breast milk in non-significant amounts without side-effects observed among breastfed infants from treated mothers. Plasma levels in those infants were shown to be low or undetectable. Penicillin is a broad spectrum antibiotic that is commonly used in Pediatrics and Neonatology with very good tolerance even in premature newborns. Be aware of false negative results that may be obtained from infants with bacterial cultures when the mother is on antibiotics. Eleventh WHO's Model List of Essential Drugs 2002: Compatible with breastfeeding.

Answer by DrLact: About UNII-Q42T66VG0C usage in lactation

Limited information indicates that UNII-Q42T66VG0C produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with penicillins, but these effects have not been adequately evaluated. UNII-Q42T66VG0C is acceptable in nursing mothers.

UNII-Q42T66VG0C Side Effects in Breastfeeding

A breastfed 1-month-old infant with congenital syphilis developed a Herxheimer reaction 6 hours after its mother received 2.4 million units of benzathine UNII-Q42T66VG0C intramuscularly. However, the baby had also received 10 units of UNII-Q42T66VG0C at about the same time as the mother's injection. The reaction was possibly caused by penicillin in breastmilk.[5]

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Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.