Is Pen-Oral Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Pen-Oral? Is Pen-Oral safe for nursing mother and child? Does Pen-Oral extracts into breast milk? Does Pen-Oral has any long term or short term side effects on infants? Can Pen-Oral influence milk supply or can Pen-Oral decrease milk supply in lactating mothers?

Pen-Oral is excreted into breast milk in non-significant amounts without side-effects observed among breastfed infants from treated mothers. Plasma levels in those infants were shown to be low or undetectable. Penicillin is a broad spectrum antibiotic that is commonly used in Pediatrics and Neonatology with very good tolerance even in premature newborns. Be aware of false negative results that may be obtained from infants with bacterial cultures when the mother is on antibiotics. Eleventh WHO's Model List of Essential Drugs 2002: Compatible with breastfeeding.

Limited information indicates that Pen-Oral produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with penicillins, but these effects have not been adequately evaluated. Pen-Oral is acceptable in nursing mothers.

In one study, 12 infants were breastfed during maternal Pen-Oral therapy. Seven appeared normal, 3 had looser stools than normal, and 1 had a rash on the buttocks on the last day of therapy. These effects were possibly related to Pen-Oral in milk, but no control group was present. One infant had stains of blood in the stool, but it had happened once prior to maternal Pen-Oral treatment.[1]