I am a breastfeeding mother and i want to know if it is safe to use Obinutuzumab? Is Obinutuzumab safe for nursing mother and child? Does Obinutuzumab extracts into breast milk? Does Obinutuzumab has any long term or short term side effects on infants? Can Obinutuzumab influence milk supply or can Obinutuzumab decrease milk supply in lactating mothers?
No information is available on the clinical use of obinutuzumab during breastfeeding. Because obinutuzumab is a large protein molecule with a molecular weight of about 150,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, obinutuzumab should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.[1] The manufacturer recommends that breastfeeding be discontinued during obinutuzumab therapy.
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