Question

I am a breastfeeding mother and i want to know if it is safe to use 1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)-? Is 1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)- safe for nursing mother and child? Does 1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)- extracts into breast milk? Does 1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)- has any long term or short term side effects on infants? Can 1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)- influence milk supply or can 1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)- decrease milk supply in lactating mothers?

1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)- lactation summary

1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)- is safe in breastfeeding
  • DrLact safety Score for 1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)- is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of 1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)- is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that 1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)- does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of 1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)- safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About 1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)- usage in lactation

One reportedly case of use by a mother for 3,5 months (8 - 12 mg x 2 / daily) without harm effects on the child. Check-up for lethargy or dyskinetic symptoms.

Answer by DrLact: About 1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)- usage in lactation

Limited information indicates that maternal doses of 1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)- up to 24 mg daily produce low levels in milk. Very limited long-term follow-up data indicate no adverse developmental effects when other phenothiazines are used alone. Monitor the infant for excessive drowsiness during breastfeeding and for developmental milestones, especially if other antipsychotics are used concurrently.

1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)- Side Effects in Breastfeeding

One infant was breastfed from 1 month to 4.5 months of age during maternal intake of 1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)- 16 mg daily. The infant grew normally and no adverse drug effects were seen.[1]

1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)- Possible Effects in Breastfeeding

Galactorrhea has been reported with 1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)-.[2][3] Hyperprolactinemia appears to be the cause of the galactorrhea.[4][5][6] The hyperprolactinemia is caused by the drug's dopamine-blocking action in the tuberoinfundibular pathway.[7] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.