Is Pioglitazona Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Pioglitazona? Is Pioglitazona safe for nursing mother and child? Does Pioglitazona extracts into breast milk? Does Pioglitazona has any long term or short term side effects on infants? Can Pioglitazona influence milk supply or can Pioglitazona decrease milk supply in lactating mothers?
Pioglitazona lactation summary
- DrLact safety Score for Pioglitazona is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Pioglitazona may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Pioglitazona may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Pioglitazona low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Pioglitazona We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Pioglitazona usage in lactation
Tiazolidindion drugs increase response to insulin.Oral anti-diabetic drugs are useless as treatment of diabetes type 1. For diabetes type 2, diet and exercise are advisable. Breastfeeding helps to lower glucemia level. See section on Maternal diabetes mellitus
Answer by DrLact: About Pioglitazona usage in lactation
No information is available on the clinical use of Pioglitazona during breastfeeding. Pioglitazona is over 99% protein bound in plasma, so it is unlikely to pass into breastmilk in clinically important amounts. If Pioglitazona is required by the mother, it is not a reason to discontinue breastfeeding. However, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Alternate Drugs
Pioglitazone(Low Risk)
Nateglinide(Unsafe)
Empagliflozin(Unsafe)
Metformin(Safe)
Dapagliflozin(Unsafe)
Insulin(Safe)
Alogliptin(Low Risk)
Glyburide(Safe)
Glipizide(Safe)
Linagliptin(Low Risk)
Sitagliptin(Low Risk)
Glimepiride(Unsafe)
Saxagliptin(Low Risk)
Chlorpropamide(Low Risk)
Colesevelam(Safe)
Acetohexamide(Low Risk)
Miglitol(Safe)
Acarbose(Safe)
Tolbutamide(Safe)
Dulaglutide(Low Risk)
Rosiglitazone(Low Risk)
Liraglutide(Low Risk)
Repaglinide(Unsafe)
Rosiglitazone(Low Risk)
Pioglitazone(Low Risk)