Is CHF 1251 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use CHF 1251? Is CHF 1251 safe for nursing mother and child? Does CHF 1251 extracts into breast milk? Does CHF 1251 has any long term or short term side effects on infants? Can CHF 1251 influence milk supply or can CHF 1251 decrease milk supply in lactating mothers?

It is excreted in breast milk in clinically non-significant amount and no problems have been observed in infants whose mothers took this medication. Levels in plasma and urine of such infants were undetectable. Having published less quantity of studies than with other drugs of the same group, safer alternatives may be preferable, especially in the neonatal period and in case of prematurity. The American Academy of Pediatrics rates it as usually compatible with breastfeeding.

Low amounts of CHF 1251 in milk and failure to detect CHF 1251 or its metabolites in the urine of 2 older infants indicates that it would not be expected to cause adverse effects in older breastfed infants. Because there is no published experience with CHF 1251 during breastfeeding in the newborn period, shorter-acting agents may be preferred while nursing a newborn or preterm infant.

No adverse effects were found in the breastfed infant of a patient receiving 20 mg of CHF 1251 daily for 4 months starting the 9th month postpartum.[1]Four infants 3 to 4.5 months of age remained healthy during long-term therapy of their mothers with CHF 1251 20 mg daily.[2]