Question

I am a breastfeeding mother and i want to know if it is safe to use NSC 666076? Is NSC 666076 safe for nursing mother and child? Does NSC 666076 extracts into breast milk? Does NSC 666076 has any long term or short term side effects on infants? Can NSC 666076 influence milk supply or can NSC 666076 decrease milk supply in lactating mothers?

NSC 666076 lactation summary

NSC 666076 is safe in breastfeeding
  • DrLact safety Score for NSC 666076 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of NSC 666076 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that NSC 666076 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of NSC 666076 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About NSC 666076 usage in lactation

It is excreted in breast milk in clinically non-significant amount and no problems have been observed in infants whose mothers took this medication. Levels in plasma and urine of such infants were undetectable. Having published less quantity of studies than with other drugs of the same group, safer alternatives may be preferable, especially in the neonatal period and in case of prematurity. The American Academy of Pediatrics rates it as usually compatible with breastfeeding.

Answer by DrLact: About NSC 666076 usage in lactation

Low amounts of NSC 666076 in milk and failure to detect NSC 666076 or its metabolites in the urine of 2 older infants indicates that it would not be expected to cause adverse effects in older breastfed infants. Because there is no published experience with NSC 666076 during breastfeeding in the newborn period, shorter-acting agents may be preferred while nursing a newborn or preterm infant.

NSC 666076 Side Effects in Breastfeeding

No adverse effects were found in the breastfed infant of a patient receiving 20 mg of NSC 666076 daily for 4 months starting the 9th month postpartum.[1]Four infants 3 to 4.5 months of age remained healthy during long-term therapy of their mothers with NSC 666076 20 mg daily.[2]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.