Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-36780APV5N? Is UNII-36780APV5N safe for nursing mother and child? Does UNII-36780APV5N extracts into breast milk? Does UNII-36780APV5N has any long term or short term side effects on infants? Can UNII-36780APV5N influence milk supply or can UNII-36780APV5N decrease milk supply in lactating mothers?

Answer by DrLact: About UNII-36780APV5N usage in lactation

If UNII-36780APV5N is required by the mother, it is not a reason to discontinue breastfeeding. Intense diuresis with large doses may decrease breastmilk production.

UNII-36780APV5N Possible Effects in Breastfeeding

UNII-36780APV5N 2 mg was given twice daily for 8 days beginning within 24 hours of delivery to suppress postpartum lactation. Patients also had breast binding for at least 10 days and fluid restriction. The authors reported that this technique was effective in 124 cases reviewed.[1] There are no data on the effects of diuretics on established lactation.

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Synonyms of UNII-36780APV5N

P 2525
P-2525
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-2-methyl-3-(((2,2,2-trifluoroethyl)thio)methyl)-, 1,1-dioxide
BRN 0770371
CCRIS 6094
6-Chloro-3,4-dihydro-2-methyl-7-sulphamoyl-3-(2,2,2-trifluoroethylthiomethyl)-2H-benzo-1,2,4-thiadiazine 1,1-dioxide
6-Chloro-3,4-dihydro-2-methyl-3-(((2,2,2-trifluoroethyl)thio)methyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Drenusil
EINECS 206-468-4
HSDB 850
2-Methyl-3-(beta,beta,beta-trifluoroethylthiomethyl)-6-chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide
Nephril
NSC 108161
Politiazida [INN-Spanish]
Polythiazidum [INN-Latin]
Renese
Politiazida
Polythiazidum
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