Is Temsirolimus Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Temsirolimus? Is Temsirolimus safe for nursing mother and child? Does Temsirolimus extracts into breast milk? Does Temsirolimus has any long term or short term side effects on infants? Can Temsirolimus influence milk supply or can Temsirolimus decrease milk supply in lactating mothers?
Answer by DrLact: About Temsirolimus usage in lactation
Temsirolimus is a prodrug of sirolimus. Because no information is available on the use of temsirolimus or sirolimus during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. The manufacturer recommends that breastfeeding be discontinued during bevacizumab therapy and for 3 weeks following the last dose.
Alternate Drugs
Pimecrolimus(Low Risk)
Methotrexate(Low Risk)
Tacrolimus(Safe)
Gemcitabine(Dangerous)
Mercaptopurine(Safe)
Cladribine(Dangerous)
Cyclosporine(Safe)
Dimethyl fumarate(Low Risk)
Azathioprine(Safe)
Everolimus(Unsafe)
Leflunomide(Dangerous)
Fluorouracil(Dangerous)
Alemtuzumab(Low Risk)
Fingolimod(Unsafe)
Sirolimus(Unsafe)