Is Vedolizumab Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Vedolizumab? Is Vedolizumab safe for nursing mother and child? Does Vedolizumab extracts into breast milk? Does Vedolizumab has any long term or short term side effects on infants? Can Vedolizumab influence milk supply or can Vedolizumab decrease milk supply in lactating mothers?

Limited information indicates that maternal vedolizumab injections produce low levels in breastmilk and does not adversely affect the nursing infant. Because vedolizumab is a large protein molecule with a molecular weight of about 147,000, absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, vedolizumab should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.

Eight women who were receiving vedolizumab for inflammatory bowel disease were breastfeeding their infants (extent not stated). Dosages were 300 mg intravenously, at 1 to 2 month intervals for 6 and starting during induction for 2 women. No increase in general or gastrointestinal tract infections were seen in the newborns up to 10 months of age and all infants reached their development milestones.[1] Five infants were breastfed by mothers receiving vedolizumab 300 mg intravenously at regular intervals. The infants all had normal developmental milestones at 3.5 to 10 months of age. All of the infants routine inactive vaccines without complications.[2]