Question

I am a breastfeeding mother and i want to know if it is safe to use Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French]? Is Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French] safe for nursing mother and child? Does Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French] extracts into breast milk? Does Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French] has any long term or short term side effects on infants? Can Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French] influence milk supply or can Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French] decrease milk supply in lactating mothers?

Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French] lactation summary

Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French] is unsafe in breastfeeding
  • DrLact safety Score for Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French] is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French] may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French] may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French] .
  • It is recommended to evaluate the advantage of not breastfeeding while using Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French] Vs not using Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French] And continue breastfeeding.
  • While using Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French] Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French] usage in lactation

May be a cause of galactorhrea by stimulting release of prolactin. Not commercially available in Spain

Answer by DrLact: About Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French] usage in lactation

Based on minimal excretion of other phenothiazine derivatives, it appears that occasional short-term use of Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French] for the treatment of nausea and vomiting poses little risk to the breastfed infant.

Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French] Possible Effects in Breastfeeding

Galactorrhea has been reported with Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French].[1] Hyperprolactinemia appears to be the cause of the galactorrhea.[2][3][4] The hyperprolactinemia is caused by the drug's dopamine-blocking action in the tuberoinfundibular pathway.[5] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
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