Question

I am a breastfeeding mother and i want to know if it is safe to use Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-? Is Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)- safe for nursing mother and child? Does Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)- extracts into breast milk? Does Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)- has any long term or short term side effects on infants? Can Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)- influence milk supply or can Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)- decrease milk supply in lactating mothers?

Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)- lactation summary

Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)- is unsafe in breastfeeding
  • DrLact safety Score for Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)- is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)- may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)- may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)- .
  • It is recommended to evaluate the advantage of not breastfeeding while using Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)- Vs not using Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)- And continue breastfeeding.
  • While using Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)- Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)- usage in lactation

May be a cause of galactorhrea by stimulting release of prolactin. Not commercially available in Spain

Answer by DrLact: About Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)- usage in lactation

Based on minimal excretion of other phenothiazine derivatives, it appears that occasional short-term use of Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)- for the treatment of nausea and vomiting poses little risk to the breastfed infant.

Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)- Possible Effects in Breastfeeding

Galactorrhea has been reported with Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-.[1] Hyperprolactinemia appears to be the cause of the galactorrhea.[2][3][4] The hyperprolactinemia is caused by the drug's dopamine-blocking action in the tuberoinfundibular pathway.[5] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
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