Is (2S,3aS,6aS)-1-((S)-N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrol-2-carbonsaeure Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use (2S,3aS,6aS)-1-((S)-N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrol-2-carbonsaeure? Is (2S,3aS,6aS)-1-((S)-N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrol-2-carbonsaeure safe for nursing mother and child? Does (2S,3aS,6aS)-1-((S)-N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrol-2-carbonsaeure extracts into breast milk? Does (2S,3aS,6aS)-1-((S)-N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrol-2-carbonsaeure has any long term or short term side effects on infants? Can (2S,3aS,6aS)-1-((S)-N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrol-2-carbonsaeure influence milk supply or can (2S,3aS,6aS)-1-((S)-N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrol-2-carbonsaeure decrease milk supply in lactating mothers?
(2S,3aS,6aS)-1-((S)-N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrol-2-carbonsaeure lactation summary
- DrLact safety Score for (2S,3aS,6aS)-1-((S)-N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrol-2-carbonsaeure is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of (2S,3aS,6aS)-1-((S)-N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrol-2-carbonsaeure may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that (2S,3aS,6aS)-1-((S)-N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrol-2-carbonsaeure may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of (2S,3aS,6aS)-1-((S)-N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrol-2-carbonsaeure low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using (2S,3aS,6aS)-1-((S)-N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrol-2-carbonsaeure We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About (2S,3aS,6aS)-1-((S)-N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrol-2-carbonsaeure usage in lactation
Answer by DrLact: About (2S,3aS,6aS)-1-((S)-N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrol-2-carbonsaeure usage in lactation
Because no information is available on the use of (2S,3aS,6aS)-1-((S)-N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrol-2-carbonsaeure during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Alternate Drugs
Ramipril(Low Risk)
Lisinopril(Low Risk)
Captopril(Safe)
Benazepril(Safe)
Fosinopril(Low Risk)
Trandolapril(Dangerous)
Enalapril(Safe)
Metoprolol(Safe)
Methyldopa(Safe)
Reserpine(Unsafe)
Diltiazem(Safe)
Losartan(Low Risk)
Levobunolol(Low Risk)
Irbesartan(Unsafe)
Ramipril(Low Risk)
Chlorthalidone(Dangerous)
Lisinopril(Low Risk)
Chlorothiazide(Safe)
Labetalol(Safe)
Isradipine(Low Risk)
Eprosartan(Low Risk)
Indapamide(Low Risk)
Doxazosin(Safe)
Captopril(Safe)
Carvedilol(Low Risk)
Bumetanide(Low Risk)
Bisoprolol(Low Risk)
Hydrochlorothiazide(Safe)
Guanfacine(Low Risk)
Hydralazine(Safe)
Nitrendipine(Safe)
Bosentan(Low Risk)
Bendroflumethiazide(Unsafe)
Atenolol(Unsafe)
Furosemide(Low Risk)
Nicardipine(Safe)
Nisoldipine(Low Risk)
Acebutolol(Unsafe)
Timolol(Safe)
Nimodipine(Safe)
Nebivolol(Unsafe)
Benazepril(Safe)
Verapamil(Safe)
Fosinopril(Low Risk)
Sotalol(Low Risk)
Nifedipine(Safe)
Amlodipine(Low Risk)
Felodipine(Low Risk)
Propranolol(Safe)
Valsartan(Low Risk)
Terazosin(Unsafe)
Trandolapril(Dangerous)
Minoxidil(Safe)
Telmisartan(Unsafe)
Torsemide(Low Risk)
Nadolol(Unsafe)
Prazosin(Unsafe)
Spironolactone(Safe)
Enalapril(Safe)