Is Risperidonum [Latin] Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Risperidonum [Latin]? Is Risperidonum [Latin] safe for nursing mother and child? Does Risperidonum [Latin] extracts into breast milk? Does Risperidonum [Latin] has any long term or short term side effects on infants? Can Risperidonum [Latin] influence milk supply or can Risperidonum [Latin] decrease milk supply in lactating mothers?

Risperidonum [Latin] and its metabolite (Paliperidone) are excreted into breast milk in non-significant amount. Untoward effect has not been observed on breastfed infants of treated mothers. Serum levels were very low or undetectable in these infants. May be a cause of galactorrhea.

Limited information indicates that maternal Risperidonum [Latin] doses of up to 6 mg daily produce low levels in milk. Because there is little published experience with Risperidonum [Latin] during breastfeeding and little long-term follow-up data, other agents may be preferred, especially while nursing a newborn or preterm infant. Systematic reviews of second-generation antipsychotics concluded that Risperidonum [Latin] seemed to be a second-line agent during breastfeeding because of the limited data available and higher excretion into milk relative to other agents.[1][2]

One woman took Risperidonum [Latin] 4 mg daily during breastfeeding. Her infant showed no developmental abnormalities on examinations up to 9 months of age. Another mother took Risperidonum [Latin] 6 mg daily during breastfeeding. Her infant showed no developmental abnormalities on examinations up to 12 months of age.[7] Two women taking Risperidonum [Latin] 4 mg and 1.5 mg daily breastfed their infants of 3.3 months and 6 weeks of age, respectively, were achieving normal developmental milestones and had no adverse effects reported.[4] A 1 week postpartum woman was started on Risperidonum [Latin] 2 mg daily and increased after 10 days to a dosage of 3 mg daily. She breastfed her infant 6 times daily. The infant was observed for 5 weeks of inpatient therapy and judged normal by a pediatric neurologist. No sedation or other adverse effects were observed in the infant. After 3 months of treatment with Risperidonum [Latin], the mother and infant were judged to be well.[5] An infant had been exclusively breastfed for 3 months during maternal therapy with Risperidonum [Latin] 1 mg daily. A pediatric examination found the infant to have no neurological or physical abnormalities, and appeared to interact appropriately.[6] In a telephone follow-up study, 124 mothers who took a benzodiazepine while nursing reported whether their infants had any signs of sedation. One mother who was taking 0.75 mg of Risperidonum [Latin] daily, flurazepam 15 mg daily, clonazepam 0.25 mg twice daily, and 1 mg of bupropion daily reported sedation in her breastfed infant.[8]

Risperidonum [Latin] has caused elevated prolactin serum levels, gynecomastia, and galactorrhea in patients taking the drug.[9][10][11][12][13][14][15] In one case, euprolactinemic gynecomastia and galactorrhea occurred in a 19-year-old man who was also taking fluvoxamine.[16] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.