Is UNII-05V02F2KDG Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use UNII-05V02F2KDG? Is UNII-05V02F2KDG safe for nursing mother and child? Does UNII-05V02F2KDG extracts into breast milk? Does UNII-05V02F2KDG has any long term or short term side effects on infants? Can UNII-05V02F2KDG influence milk supply or can UNII-05V02F2KDG decrease milk supply in lactating mothers?
UNII-05V02F2KDG lactation summary
- DrLact safety Score for UNII-05V02F2KDG is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of UNII-05V02F2KDG may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that UNII-05V02F2KDG may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of UNII-05V02F2KDG low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using UNII-05V02F2KDG We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About UNII-05V02F2KDG usage in lactation
Tiazolidindion drugs increase the response to insulin.Oral anti-diabetic drugs are useless for treatment of diabetes type 1. For diabetes type 2, diet and exercise are advisable. Breastfeeding helps to lower glucemia level. See section on Maternal diabetes mellitus
Answer by DrLact: About UNII-05V02F2KDG usage in lactation
No information is available on the clinical use of UNII-05V02F2KDG during breastfeeding. UNII-05V02F2KDG is over 99% protein bound in plasma, so it is unlikely to pass into breastmilk in clinically important amounts. The manufacturer recommends avoiding breastfeeding during UNII-05V02F2KDG use, so pioglitazone might be a better choice of the drugs in this class for nursing mothers.
Alternate Drugs
Repaglinide(Unsafe)
Pioglitazone(Low Risk)
Nateglinide(Unsafe)
Empagliflozin(Unsafe)
Dapagliflozin(Unsafe)
Metformin(Safe)
Alogliptin(Low Risk)
Insulin(Safe)
Glyburide(Safe)
Linagliptin(Low Risk)
Glipizide(Safe)
Sitagliptin(Low Risk)
Glimepiride(Unsafe)
Saxagliptin(Low Risk)
Chlorpropamide(Low Risk)
Colesevelam(Safe)
Acetohexamide(Low Risk)
Miglitol(Safe)
Acarbose(Safe)
Tolbutamide(Safe)
Dulaglutide(Low Risk)
Rosiglitazone(Low Risk)
Liraglutide(Low Risk)
Pioglitazone(Low Risk)
Rosiglitazone(Low Risk)