I am a breastfeeding mother and i want to know if it is safe to use Pembrolizumab? Is Pembrolizumab safe for nursing mother and child? Does Pembrolizumab extracts into breast milk? Does Pembrolizumab has any long term or short term side effects on infants? Can Pembrolizumab influence milk supply or can Pembrolizumab decrease milk supply in lactating mothers?
No information is available on the clinical use of pembrolizumab during breastfeeding. Because pembrolizumab is a large protein molecule with a molecular weight of about 149,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, pembrolizumab should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. The manufacturer recommends that breastfeeding be discontinued during pembrolizumab therapy and for 4 months after the last dose.
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