Question

I am a breastfeeding mother and i want to know if it is safe to use AT-4140? Is AT-4140 safe for nursing mother and child? Does AT-4140 extracts into breast milk? Does AT-4140 has any long term or short term side effects on infants? Can AT-4140 influence milk supply or can AT-4140 decrease milk supply in lactating mothers?

Answer by DrLact: About AT-4140 usage in lactation

No information is available on the use of AT-4140 during breastfeeding. Fluoroquinolones have traditionally not been used in infants because of concern about adverse effects on the infants' developing joints. However, recent studies indicate little risk.[1][2] The calcium in milk might prevent absorption of the small amounts of fluoroquinolones in milk,[3] but insufficient data exist to prove or disprove this assertion. Use of AT-4140 is acceptable in nursing mothers with monitoring of the infant for possible effects on the gastrointestinal flora, such as diarrhea or candidiasis (thrush, diaper rash). However, it is preferable to use an alternate drug for which safety information is available.

Alternate Drugs

Dapsone(Low Risk)
Rifaximin(Safe)
Meropenem(Safe)
Capreomycin(Low Risk)
Valganciclovir(Low Risk)
Famciclovir(Low Risk)
Cefixime(Safe)
Ganciclovir(Low Risk)
Neomycin(Safe)
Acyclovir(Safe)
Ertapenem(Safe)
Erythromycin(Low Risk)
Cefepime(Safe)
Quinine(Safe)
Indinavir(Unsafe)
Zidovudine(Low Risk)
Aztreonam(Safe)
Econazole(Safe)
Amantadine(Low Risk)
Gatifloxacin(Low Risk)
Cefprozil(Safe)
Tenofovir(Safe)
Nafcillin(Safe)
Cefdinir(Safe)
Lindane(Unsafe)
Lomefloxacin(Low Risk)
Cefazolin(Safe)
Enoxacin(Low Risk)
Efavirenz(Unsafe)
Cefoxitin(Safe)
Saquinavir(Unsafe)
Moxifloxacin(Low Risk)
Primaquine(Low Risk)
Didanosine(Unsafe)
Malathion(Low Risk)
Atovaquone(Low Risk)
Doxycycline(Low Risk)
Ofloxacin(Safe)
Cefotetan(Safe)
Levofloxacin(Low Risk)
Linezolid(Low Risk)
Ritonavir(Unsafe)
Cefaclor(Safe)
Kanamycin(Safe)
Naftifine(Safe)
Methicillin(Low Risk)
Abacavir(Safe)
Nevirapine(Low Risk)
Amikacin(Safe)
Demeclocycline(Low Risk)
Clindamycin(Low Risk)
Nelfinavir(Unsafe)
Cefixime(Safe)
Capreomycin(Low Risk)
Neomycin(Safe)
Ertapenem(Safe)
Erythromycin(Low Risk)
Iodine(Unsafe)
Cefepime(Safe)
Aztreonam(Safe)
Clindamycin(Low Risk)
Nalidixic Acid(Low Risk)
Gatifloxacin(Low Risk)
Cefprozil(Safe)
Nafcillin(Safe)
Lomefloxacin(Low Risk)
Cefdinir(Safe)
Cefazolin(Safe)
Enoxacin(Low Risk)
Cefoxitin(Safe)
Moxifloxacin(Low Risk)
Doxycycline(Low Risk)
Ofloxacin(Safe)
Cefotetan(Safe)
Levofloxacin(Low Risk)
Cefaclor(Safe)
Kanamycin(Safe)
Methicillin(Low Risk)
Demeclocycline(Low Risk)
Mupirocin(Safe)
Methenamine(Unsafe)
Amikacin(Safe)
Gatifloxacin(Low Risk)
Lomefloxacin(Low Risk)
Enoxacin(Low Risk)
Moxifloxacin(Low Risk)
Ofloxacin(Safe)
Levofloxacin(Low Risk)
Nalidixic Acid(Low Risk)
Gatifloxacin(Low Risk)
Lomefloxacin(Low Risk)
Enoxacin(Low Risk)
Moxifloxacin(Low Risk)
Ofloxacin(Safe)
Levofloxacin(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.