Is Blinatumomab Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Blinatumomab? Is Blinatumomab safe for nursing mother and child? Does Blinatumomab extracts into breast milk? Does Blinatumomab has any long term or short term side effects on infants? Can Blinatumomab influence milk supply or can Blinatumomab decrease milk supply in lactating mothers?
Answer by DrLact: About Blinatumomab usage in lactation
No information is available on the clinical use of blinatumomab during breastfeeding. Because blinatumomab is a large protein molecule with a molecular weight of about 54,000 the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, blinatumomab should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. The manufacturer recommends that breastfeeding be discontinued during blinatumomab therapy and for at least 48 hours after treatment.
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