Question

I am a breastfeeding mother and i want to know if it is safe to use Brican? Is Brican safe for nursing mother and child? Does Brican extracts into breast milk? Does Brican has any long term or short term side effects on infants? Can Brican influence milk supply or can Brican decrease milk supply in lactating mothers?

Brican lactation summary

Brican is safe in breastfeeding
  • DrLact safety Score for Brican is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Brican is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Brican does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Brican safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Brican usage in lactation

It is excreted into breast milk in clinically non-significant amount and neither clinical nor development problems were observed in infants whose mothers were treated with oral Brican.Plasma levels of these infants were undetectable or very low. Preferable preparations are inhaled bronchodilators since <10% of the dose is absorbed. American Academy of Pediatrics: medication usually compatible with breastfeeding.

Answer by DrLact: About Brican usage in lactation

Maternal use of oral or inhaled Brican is unlikely to affect a breastfed infant. The authors of several reviews and an expert panel agree that use of inhaled bronchodilators is acceptable during breastfeeding because of the low bioavailability and maternal serum levels after use.[1][2][3][4][5] Brican use as a tocolytic agent might decrease the duration of breastfeeding.

Brican Side Effects in Breastfeeding

Two papers have reported a total of 4 infants aged 3 to 8 weeks who were breastfed during maternal use of oral Brican 2.5 or 5 mg three times daily. None of the infants had any signs of sympathetic stimulation and all were developing normally.[6][7] These cases were also summarized in a third publication.[8]

Brican Possible Effects in Breastfeeding

A small retrospective survey from Serbia found that mothers who received a beta agonist pharmacologically similar to Brican (fenoterol or hexoprenaline) as a tocolytic breastfed for a shorter period of time than those who received no tocolytic (4.5 vs 9.5 months).[9] It is not known if Brican has a similar effect.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.