Question

I am a breastfeeding mother and i want to know if it is safe to use EINECS 245-385-8? Is EINECS 245-385-8 safe for nursing mother and child? Does EINECS 245-385-8 extracts into breast milk? Does EINECS 245-385-8 has any long term or short term side effects on infants? Can EINECS 245-385-8 influence milk supply or can EINECS 245-385-8 decrease milk supply in lactating mothers?

EINECS 245-385-8 lactation summary

EINECS 245-385-8 is safe in breastfeeding
  • DrLact safety Score for EINECS 245-385-8 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of EINECS 245-385-8 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that EINECS 245-385-8 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of EINECS 245-385-8 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About EINECS 245-385-8 usage in lactation

It is excreted into breast milk in clinically non-significant amount and neither clinical nor development problems were observed in infants whose mothers were treated with oral EINECS 245-385-8.Plasma levels of these infants were undetectable or very low. Preferable preparations are inhaled bronchodilators since <10% of the dose is absorbed. American Academy of Pediatrics: medication usually compatible with breastfeeding.

Answer by DrLact: About EINECS 245-385-8 usage in lactation

Maternal use of oral or inhaled EINECS 245-385-8 is unlikely to affect a breastfed infant. The authors of several reviews and an expert panel agree that use of inhaled bronchodilators is acceptable during breastfeeding because of the low bioavailability and maternal serum levels after use.[1][2][3][4][5] EINECS 245-385-8 use as a tocolytic agent might decrease the duration of breastfeeding.

EINECS 245-385-8 Side Effects in Breastfeeding

Two papers have reported a total of 4 infants aged 3 to 8 weeks who were breastfed during maternal use of oral EINECS 245-385-8 2.5 or 5 mg three times daily. None of the infants had any signs of sympathetic stimulation and all were developing normally.[6][7] These cases were also summarized in a third publication.[8]

EINECS 245-385-8 Possible Effects in Breastfeeding

A small retrospective survey from Serbia found that mothers who received a beta agonist pharmacologically similar to EINECS 245-385-8 (fenoterol or hexoprenaline) as a tocolytic breastfed for a shorter period of time than those who received no tocolytic (4.5 vs 9.5 months).[9] It is not known if EINECS 245-385-8 has a similar effect.
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