Is Dinutuximab Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Dinutuximab? Is Dinutuximab safe for nursing mother and child? Does Dinutuximab extracts into breast milk? Does Dinutuximab has any long term or short term side effects on infants? Can Dinutuximab influence milk supply or can Dinutuximab decrease milk supply in lactating mothers?
Answer by DrLact: About Dinutuximab usage in lactation
No information is available on the clinical use of dinutuximab during breastfeeding. Because dinutuximab is a large protein molecule with a molecular weight of about 150,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, dinutuximab should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. The manufacturer recommends that breastfeeding be discontinued during dinutuximab therapy.
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