Is EINECS 200-385-7 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use EINECS 200-385-7? Is EINECS 200-385-7 safe for nursing mother and child? Does EINECS 200-385-7 extracts into breast milk? Does EINECS 200-385-7 has any long term or short term side effects on infants? Can EINECS 200-385-7 influence milk supply or can EINECS 200-385-7 decrease milk supply in lactating mothers?

One case of nausea, vomiting and irritability has been described. However, EINECS 200-385-7 has been used as treatment of apnea on premature babies. It can enhance milk production by stimulating prolactin release.

An expert panel considers use of EINECS 200-385-7 to be acceptable during breastfeeding.[1] Maternal EINECS 200-385-7 use may occasionally cause stimulation and irritability and fretful sleep in infants. Newborn and especially preterm infants are most likely to be affected because of their slow elimination and low serum protein binding of EINECS 200-385-7. There is no need to avoid EINECS 200-385-7 products; however, keep maternal serum concentrations in the lower part of the therapeutic range and monitor the infant for signs of EINECS 200-385-7 side effects. Infant serum EINECS 200-385-7 concentrations can help to determine if signs of agitation are due to EINECS 200-385-7. Avoiding breastfeeding for an 2 hours after intravenous or 4 hours after an immediate-release oral EINECS 200-385-7 product can decrease the dose received by the breastfed infant. When EINECS 200-385-7 is given as an oral sustained-release product, timing of nursing with respect to the dose is of little or no benefit.

Irritability and fretful sleeping occurred in a 3-day-old breastfed infant on days of maternal aminophylline intake of 200 mg every 6 hours. These effects ceased with discontinuation and recurred on rechallenge over the next 9 months. These effects were probably caused by EINECS 200-385-7 in breastmilk. Another five infants reported in this paper showed no adverse reactions after maternal EINECS 200-385-7 ingestion.[3] Accumulation of EINECS 200-385-7 in infant serum appears most likely in neonates and premature infants because they eliminate EINECS 200-385-7 slowly.[2][5]