Question

I am a breastfeeding mother and i want to know if it is safe to use Theo-24? Is Theo-24 safe for nursing mother and child? Does Theo-24 extracts into breast milk? Does Theo-24 has any long term or short term side effects on infants? Can Theo-24 influence milk supply or can Theo-24 decrease milk supply in lactating mothers?

Theo-24 lactation summary

Theo-24 is safe in breastfeeding
  • DrLact safety Score for Theo-24 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Theo-24 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Theo-24 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Theo-24 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Theo-24 usage in lactation

One case of nausea, vomiting and irritability has been described. However, Theo-24 has been used as treatment of apnea on premature babies. It can enhance milk production by stimulating prolactin release.

Answer by DrLact: About Theo-24 usage in lactation

An expert panel considers use of Theo-24 to be acceptable during breastfeeding.[1] Maternal Theo-24 use may occasionally cause stimulation and irritability and fretful sleep in infants. Newborn and especially preterm infants are most likely to be affected because of their slow elimination and low serum protein binding of Theo-24. There is no need to avoid Theo-24 products; however, keep maternal serum concentrations in the lower part of the therapeutic range and monitor the infant for signs of Theo-24 side effects. Infant serum Theo-24 concentrations can help to determine if signs of agitation are due to Theo-24. Avoiding breastfeeding for an 2 hours after intravenous or 4 hours after an immediate-release oral Theo-24 product can decrease the dose received by the breastfed infant. When Theo-24 is given as an oral sustained-release product, timing of nursing with respect to the dose is of little or no benefit.

Theo-24 Side Effects in Breastfeeding

Irritability and fretful sleeping occurred in a 3-day-old breastfed infant on days of maternal aminophylline intake of 200 mg every 6 hours. These effects ceased with discontinuation and recurred on rechallenge over the next 9 months. These effects were probably caused by Theo-24 in breastmilk. Another five infants reported in this paper showed no adverse reactions after maternal Theo-24 ingestion.[3] Accumulation of Theo-24 in infant serum appears most likely in neonates and premature infants because they eliminate Theo-24 slowly.[2][5]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.