Question

I am a breastfeeding mother and i want to know if it is safe to use Theodur? Is Theodur safe for nursing mother and child? Does Theodur extracts into breast milk? Does Theodur has any long term or short term side effects on infants? Can Theodur influence milk supply or can Theodur decrease milk supply in lactating mothers?

Theodur lactation summary

Theodur is safe in breastfeeding
  • DrLact safety Score for Theodur is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Theodur is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Theodur does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Theodur safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Theodur usage in lactation

One case of nausea, vomiting and irritability has been described. However, Theodur has been used as treatment of apnea on premature babies. It can enhance milk production by stimulating prolactin release.

Answer by DrLact: About Theodur usage in lactation

An expert panel considers use of Theodur to be acceptable during breastfeeding.[1] Maternal Theodur use may occasionally cause stimulation and irritability and fretful sleep in infants. Newborn and especially preterm infants are most likely to be affected because of their slow elimination and low serum protein binding of Theodur. There is no need to avoid Theodur products; however, keep maternal serum concentrations in the lower part of the therapeutic range and monitor the infant for signs of Theodur side effects. Infant serum Theodur concentrations can help to determine if signs of agitation are due to Theodur. Avoiding breastfeeding for an 2 hours after intravenous or 4 hours after an immediate-release oral Theodur product can decrease the dose received by the breastfed infant. When Theodur is given as an oral sustained-release product, timing of nursing with respect to the dose is of little or no benefit.

Theodur Side Effects in Breastfeeding

Irritability and fretful sleeping occurred in a 3-day-old breastfed infant on days of maternal aminophylline intake of 200 mg every 6 hours. These effects ceased with discontinuation and recurred on rechallenge over the next 9 months. These effects were probably caused by Theodur in breastmilk. Another five infants reported in this paper showed no adverse reactions after maternal Theodur ingestion.[3] Accumulation of Theodur in infant serum appears most likely in neonates and premature infants because they eliminate Theodur slowly.[2][5]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.