Question

I am a breastfeeding mother and i want to know if it is safe to use EINECS 215-819-0? Is EINECS 215-819-0 safe for nursing mother and child? Does EINECS 215-819-0 extracts into breast milk? Does EINECS 215-819-0 has any long term or short term side effects on infants? Can EINECS 215-819-0 influence milk supply or can EINECS 215-819-0 decrease milk supply in lactating mothers?

EINECS 215-819-0 lactation summary

EINECS 215-819-0 is unsafe in breastfeeding
  • DrLact safety Score for EINECS 215-819-0 is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of EINECS 215-819-0 may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that EINECS 215-819-0 may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using EINECS 215-819-0 .
  • It is recommended to evaluate the advantage of not breastfeeding while using EINECS 215-819-0 Vs not using EINECS 215-819-0 And continue breastfeeding.
  • While using EINECS 215-819-0 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About EINECS 215-819-0 usage in lactation

It is a first generation antihistaminic and phenothiazine drug with a sedative effect. Isolated dose is considered to be compatible with BF. Used in Ménière’s disease, we suggest to choose a alternative safer drug.

Answer by DrLact: About EINECS 215-819-0 usage in lactation

Based on minimal excretion of other phenothiazine derivatives, it appears that occasional short-term use of EINECS 215-819-0 for the treatment of nausea and vomiting poses little risk to the breastfed infant.

EINECS 215-819-0 Possible Effects in Breastfeeding

Phenothiazines cause galactorrhea in 26 to 40% of female patients.[1][2] Hyperprolactinemia appears to be the cause of the galactorrhea.[3][4][5] The hyperprolactinemia is caused by the drug's dopamine-blocking action in the tuberoinfundibular pathway.[6]
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