Is HSDB 3400 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use HSDB 3400? Is HSDB 3400 safe for nursing mother and child? Does HSDB 3400 extracts into breast milk? Does HSDB 3400 has any long term or short term side effects on infants? Can HSDB 3400 influence milk supply or can HSDB 3400 decrease milk supply in lactating mothers?

• DrLact safety Score for HSDB 3400 is 5 out of 8 which is considered Unsafe as per our analyses.
• A safety Score of 5 indicates that usage of HSDB 3400 may cause serious side effects in breastfed baby.
• Our study of different scientific research indicates that HSDB 3400 may cause moderate to high side effects or may affect milk supply in lactating mother.
• Our suggestion is to use safer alternate options rather than using HSDB 3400 .
• It is recommended to evaluate the advantage of not breastfeeding while using HSDB 3400 Vs not using HSDB 3400 And continue breastfeeding.
• While using HSDB 3400 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
• Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

It is a first generation antihistaminic and phenothiazine drug with a sedative effect. Isolated dose is considered to be compatible with BF. Used in Ménière’s disease, we suggest to choose a alternative safer drug.

Based on minimal excretion of other phenothiazine derivatives, it appears that occasional short-term use of HSDB 3400 for the treatment of nausea and vomiting poses little risk to the breastfed infant.

Phenothiazines cause galactorrhea in 26 to 40% of female patients.[1][2] Hyperprolactinemia appears to be the cause of the galactorrhea.[3][4][5] The hyperprolactinemia is caused by the drug's dopamine-blocking action in the tuberoinfundibular pathway.[6]