Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-8ETK1WAF6R? Is UNII-8ETK1WAF6R safe for nursing mother and child? Does UNII-8ETK1WAF6R extracts into breast milk? Does UNII-8ETK1WAF6R has any long term or short term side effects on infants? Can UNII-8ETK1WAF6R influence milk supply or can UNII-8ETK1WAF6R decrease milk supply in lactating mothers?

UNII-8ETK1WAF6R lactation summary

UNII-8ETK1WAF6R is unsafe in breastfeeding
  • DrLact safety Score for UNII-8ETK1WAF6R is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of UNII-8ETK1WAF6R may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that UNII-8ETK1WAF6R may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using UNII-8ETK1WAF6R .
  • It is recommended to evaluate the advantage of not breastfeeding while using UNII-8ETK1WAF6R Vs not using UNII-8ETK1WAF6R And continue breastfeeding.
  • While using UNII-8ETK1WAF6R Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About UNII-8ETK1WAF6R usage in lactation

It is a first generation antihistaminic and phenothiazine drug with a sedative effect. Isolated dose is considered to be compatible with BF. Used in Ménière’s disease, we suggest to choose a alternative safer drug.

Answer by DrLact: About UNII-8ETK1WAF6R usage in lactation

Based on minimal excretion of other phenothiazine derivatives, it appears that occasional short-term use of UNII-8ETK1WAF6R for the treatment of nausea and vomiting poses little risk to the breastfed infant.

UNII-8ETK1WAF6R Possible Effects in Breastfeeding

Phenothiazines cause galactorrhea in 26 to 40% of female patients.[1][2] Hyperprolactinemia appears to be the cause of the galactorrhea.[3][4][5] The hyperprolactinemia is caused by the drug's dopamine-blocking action in the tuberoinfundibular pathway.[6]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.