Question

I am a breastfeeding mother and i want to know if it is safe to use Mepolizumab? Is Mepolizumab safe for nursing mother and child? Does Mepolizumab extracts into breast milk? Does Mepolizumab has any long term or short term side effects on infants? Can Mepolizumab influence milk supply or can Mepolizumab decrease milk supply in lactating mothers?

Answer by DrLact: About Mepolizumab usage in lactation

No information is available on the clinical use of mepolizumab during breastfeeding. Because mepolizumab is a large protein molecule with a molecular weight of 149,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, mepolizumab should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.
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