Question

I am a breastfeeding mother and i want to know if it is safe to use Mellerette? Is Mellerette safe for nursing mother and child? Does Mellerette extracts into breast milk? Does Mellerette has any long term or short term side effects on infants? Can Mellerette influence milk supply or can Mellerette decrease milk supply in lactating mothers?

Mellerette lactation summary

Mellerette is unsafe in breastfeeding
  • DrLact safety Score for Mellerette is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of Mellerette may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that Mellerette may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using Mellerette .
  • It is recommended to evaluate the advantage of not breastfeeding while using Mellerette Vs not using Mellerette And continue breastfeeding.
  • While using Mellerette Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Mellerette usage in lactation

No data on transfer into breastmilk are available. Withdrawn from the market in 2005 because of an increased risk of ventricular arrhytmias.

Answer by DrLact: About Mellerette usage in lactation

Because there is no published experience with Mellerette during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Mellerette Possible Effects in Breastfeeding

Phenothiazines cause galactorrhea in 26 to 40% of female patients.[1][2] Hyperprolactinemia appears to be the cause of the galactorrhea.[3][4][5] There is some evidence that Mellerette increases serum prolactin to a greater extent than other phenothiazines.[6] The hyperprolactinemia is caused by the drug's dopamine-blocking action in the tuberoinfundibular pathway.[7] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.