Question

I am a breastfeeding mother and i want to know if it is safe to use Melleril (liquid)? Is Melleril (liquid) safe for nursing mother and child? Does Melleril (liquid) extracts into breast milk? Does Melleril (liquid) has any long term or short term side effects on infants? Can Melleril (liquid) influence milk supply or can Melleril (liquid) decrease milk supply in lactating mothers?

Melleril (liquid) lactation summary

Melleril (liquid) is unsafe in breastfeeding
  • DrLact safety Score for Melleril (liquid) is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of Melleril (liquid) may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that Melleril (liquid) may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using Melleril (liquid) .
  • It is recommended to evaluate the advantage of not breastfeeding while using Melleril (liquid) Vs not using Melleril (liquid) And continue breastfeeding.
  • While using Melleril (liquid) Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Melleril (liquid) usage in lactation

No data on transfer into breastmilk are available. Withdrawn from the market in 2005 because of an increased risk of ventricular arrhytmias.

Answer by DrLact: About Melleril (liquid) usage in lactation

Because there is no published experience with Melleril (liquid) during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Melleril (liquid) Possible Effects in Breastfeeding

Phenothiazines cause galactorrhea in 26 to 40% of female patients.[1][2] Hyperprolactinemia appears to be the cause of the galactorrhea.[3][4][5] There is some evidence that Melleril (liquid) increases serum prolactin to a greater extent than other phenothiazines.[6] The hyperprolactinemia is caused by the drug's dopamine-blocking action in the tuberoinfundibular pathway.[7] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.