Question

I am a breastfeeding mother and i want to know if it is safe to use Thioridazin? Is Thioridazin safe for nursing mother and child? Does Thioridazin extracts into breast milk? Does Thioridazin has any long term or short term side effects on infants? Can Thioridazin influence milk supply or can Thioridazin decrease milk supply in lactating mothers?

Thioridazin lactation summary

Thioridazin is unsafe in breastfeeding
  • DrLact safety Score for Thioridazin is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of Thioridazin may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that Thioridazin may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using Thioridazin .
  • It is recommended to evaluate the advantage of not breastfeeding while using Thioridazin Vs not using Thioridazin And continue breastfeeding.
  • While using Thioridazin Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Thioridazin usage in lactation

No data on transfer into breastmilk are available. Withdrawn from the market in 2005 because of an increased risk of ventricular arrhytmias.

Answer by DrLact: About Thioridazin usage in lactation

Because there is no published experience with Thioridazin during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Thioridazin Possible Effects in Breastfeeding

Phenothiazines cause galactorrhea in 26 to 40% of female patients.[1][2] Hyperprolactinemia appears to be the cause of the galactorrhea.[3][4][5] There is some evidence that Thioridazin increases serum prolactin to a greater extent than other phenothiazines.[6] The hyperprolactinemia is caused by the drug's dopamine-blocking action in the tuberoinfundibular pathway.[7] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.