Question

I am a breastfeeding mother and i want to know if it is safe to use NSC 108165? Is NSC 108165 safe for nursing mother and child? Does NSC 108165 extracts into breast milk? Does NSC 108165 has any long term or short term side effects on infants? Can NSC 108165 influence milk supply or can NSC 108165 decrease milk supply in lactating mothers?

NSC 108165 lactation summary

NSC 108165 is unsafe in breastfeeding
  • DrLact safety Score for NSC 108165 is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of NSC 108165 may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that NSC 108165 may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using NSC 108165 .
  • It is recommended to evaluate the advantage of not breastfeeding while using NSC 108165 Vs not using NSC 108165 And continue breastfeeding.
  • While using NSC 108165 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About NSC 108165 usage in lactation

No data on transfer into breastmilk are available.

Answer by DrLact: About NSC 108165 usage in lactation

Because there is no published experience with NSC 108165 during breastfeeding, other antipsychotic agents are preferred.

NSC 108165 Possible Effects in Breastfeeding

NSC 108165 has caused galactorrhea.[1] Hyperprolactinemia appears to be the cause of the galactorrhea.[2][3][4] The hyperprolactinemia is caused by the drug's dopamine-blocking action in the tuberoinfundibular pathway.[5] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.