Is Sodium Oxybate Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Sodium Oxybate? Is Sodium Oxybate safe for nursing mother and child? Does Sodium Oxybate extracts into breast milk? Does Sodium Oxybate has any long term or short term side effects on infants? Can Sodium Oxybate influence milk supply or can Sodium Oxybate decrease milk supply in lactating mothers?

Sodium salt of gamma-hydroxybutyric acid (GHBA), a natural body substance normally found in milk at levels of 0.1 - 1 mg / L.It is used for the treatment of narcolepsy. Given its rapid half-life, after 4 to 5 hours the GHBA levels in milk are back in the normal range.Since it is administered in two evening doses at the beginning of the night (22:00 h and 02:00 h) breastfeeding is allowed even exclusively, taking care to wait 4 hours after the last dose. It would be advisable to pump breast milk during the day for using it at night time.The intestinal drug absorption and plasma levels decrease significantly (up 58%) with simultaneous administration of a meal, especially if it has a high fat content. They have not been observed problems in infants whose mothers were on this treatment. At least, one infant was exclusively breastfed for 6 months while her mother was taking sodium oxybate, fluoxetine and cetirizine with a pausing of 4 hours after each of the two doses of oxybate. Oxybate does not alter prolactin levels. See below the information of these related products:

Sodium oxybate is the sodium salt of gamma-hydroxybutyric acid (GHB). GHB is an endogenous substance and low amounts are normally found in breastmilk. Large doses of GHB have been used as a substance of abuse. Infants have been successfully breastfed by mothers taking sodium oxybate therapeutically for narcolepsy. With the typical 2 doses per night treatment regimen, nursing should usually be withheld from the time of the first dose to 4 to 6 hours after the second dose and breastfeeding can be continued during the day.[1] No information is available on the use or safety of GHB as a drug of abuse during breastfeeding.

A woman was taking 4.5 grams of sodium oxybate twice daily (exact times not reported) for narcolepsy and cataplexy throughout pregnancy and lactation. She breastfed her infant (extent and times not stated). No adverse infant effects were reported.[2] A woman with narcolepsy took sodium oxybate 4 grams each night at 10 pm and 2 am as well as fluoxetine 20 mg and cetirizine 5 mg daily throughout pregnancy and postpartum. She breastfed her infant except for 4 hours after the 10 pm oxybate dose and 4 hours after the 2 am dose. She either pumped breastmilk or breastfed her infant just before each dose of oxybate. The infant was exclusively breastfed or breastmilk fed for 6 months when solids were introduced. The infant was evaluated at 2, 4 and 6 months with the Ages and Stages Questionnaires, which were withing the normal range as were the infant's growth and pediatrician's clinical impressions regarding the infant's growth and development.[5]