Question

I am a breastfeeding mother and i want to know if it is safe to use AC 4464? Is AC 4464 safe for nursing mother and child? Does AC 4464 extracts into breast milk? Does AC 4464 has any long term or short term side effects on infants? Can AC 4464 influence milk supply or can AC 4464 decrease milk supply in lactating mothers?

AC 4464 lactation summary

AC 4464 usage has low risk in breastfeeding
  • DrLact safety Score for AC 4464 is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of AC 4464 may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that AC 4464 may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of AC 4464 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using AC 4464 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About AC 4464 usage in lactation

Loop diuretic. Long-term treatment with diuretic drugs (particularly those Thiazides with long lasting effect and loop-acting drugs) may inhibit lactation. Use a lower dose as possible, especially during the first postnatal month.

Answer by DrLact: About AC 4464 usage in lactation

Because no information is available on the use of AC 4464 during breastfeeding and because intense diuresis might decrease lactation, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

AC 4464 Possible Effects in Breastfeeding

Relevant published information on AC 4464 was not found as of the revision date. Intense diuresis, fluid restriction and breast binding have been used to suppress lactation immediately postpartum.[1][2][3] The added contribution of the diuretic to the other measures, which are effective in suppressing lactation, has not been studied. No data exist on the effects of loop diuretics on established, ongoing lactation.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.