Is 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea? Is 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea safe for nursing mother and child? Does 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea extracts into breast milk? Does 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea has any long term or short term side effects on infants? Can 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea influence milk supply or can 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea decrease milk supply in lactating mothers?
1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea lactation summary
- DrLact safety Score for 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea usage in lactation
Loop diuretic. Long-term treatment with diuretic drugs (particularly those Thiazides with long lasting effect and loop-acting drugs) may inhibit lactation. Use a lower dose as possible, especially during the first postnatal month.
Answer by DrLact: About 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea usage in lactation
Because no information is available on the use of 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea during breastfeeding and because intense diuresis might decrease lactation, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea Possible Effects in Breastfeeding
Relevant published information on 1-Isopropyl-3-((4-m-toluidino-3-pyridyl)sulfonyl)urea was not found as of the revision date. Intense diuresis, fluid restriction and breast binding have been used to suppress lactation immediately postpartum.[1][2][3] The added contribution of the diuretic to the other measures, which are effective in suppressing lactation, has not been studied. No data exist on the effects of loop diuretics on established, ongoing lactation.
Alternate Drugs
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Nisoldipine(Low Risk)
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