Is Daclizumab Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Daclizumab? Is Daclizumab safe for nursing mother and child? Does Daclizumab extracts into breast milk? Does Daclizumab has any long term or short term side effects on infants? Can Daclizumab influence milk supply or can Daclizumab decrease milk supply in lactating mothers?
Daclizumab lactation summary
- DrLact safety Score for Daclizumab is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Daclizumab may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Daclizumab may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Daclizumab low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Daclizumab We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Daclizumab usage in lactation
Used for prevention of kidney transplant rejection.
Answer by DrLact: About Daclizumab usage in lactation
No information is available on the clinical use of daclizumab during breastfeeding. Because daclizumab is a large protein molecule with a molecular weight of about 144,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, daclizumab should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. Some authors recommend avoiding breastfeeding with daclizumab.[1][2]