Is HSDB 3195 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use HSDB 3195? Is HSDB 3195 safe for nursing mother and child? Does HSDB 3195 extracts into breast milk? Does HSDB 3195 has any long term or short term side effects on infants? Can HSDB 3195 influence milk supply or can HSDB 3195 decrease milk supply in lactating mothers?

Tranquillizer drug similar to prochlorperazine that may produce galactorrhea by increasing prolactin release.

Limited information indicates that maternal doses of HSDB 3195 up to 10 mg daily do not affect the breastfed infant. Very limited long-term follow-up data indicate no adverse developmental effects when other phenothiazines are used alone. Because there is little published experience with HSDB 3195 during breastfeeding, other antipsychotic agents may be preferred, especially wile nursing an newborn or preterm infant.

One infant was breastfed from birth during maternal HSDB 3195 10 mg daily in addition to clonazepam 0.25 mg daily and valproic acid 500 mg daily. No adverse effects in the infant were reported by the mother (follow-up time unspecified).[2] One mother began taking HSDB 3195 (dosage unspecified) 2 months postpartum while breastfeeding her infant. She also started olanzapine 10 mg daily, paroxetine and procyclidine (dosages unspecified). The infant experiences no adverse reactions.[3] Two mothers taking HSDB 3195 5 and 10 mg per day orally breastfed their infants from 1 week and 8 weeks of age, respectively. Mental and psychomotor development were measured at various time up to 30 months of age and were found to be normal.[1]

Phenothiazines cause galactorrhea in 26 to 40% of female patients.[4][5] Hyperprolactinemia appears to be the cause of the galactorrhea.[6][7][8] The hyperprolactinemia is caused by the drug's dopamine-blocking action in the tuberoinfundibular pathway.[9]