Question

I am a breastfeeding mother and i want to know if it is safe to use NSC 272306NA? Is NSC 272306NA safe for nursing mother and child? Does NSC 272306NA extracts into breast milk? Does NSC 272306NA has any long term or short term side effects on infants? Can NSC 272306NA influence milk supply or can NSC 272306NA decrease milk supply in lactating mothers?

NSC 272306NA lactation summary

NSC 272306NA is safe in breastfeeding
  • DrLact safety Score for NSC 272306NA is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of NSC 272306NA is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that NSC 272306NA does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of NSC 272306NA safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About NSC 272306NA usage in lactation

It is excreted in breast milk in clinically non-significant amount and no problems have been observed in infants whose mothers were receiving this treatment.Plasma levels in these infants were undetectable or very low. NSC 272306NA may induce to an increase of plasma Prolactin levels. American Academy of Pediatrics: usually compatible with breastfeeding medication.WHO List of Essential Medicines 2002: compatible with breastfeeding.

Answer by DrLact: About NSC 272306NA usage in lactation

Limited information indicates that maternal doses of NSC 272306NA up to 360 mg daily produce low levels in milk and newborns may have detectable NSC 272306NA serum levels, but levels are low. NSC 272306NA would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months.

NSC 272306NA Side Effects in Breastfeeding

No adverse reactions have been reported among 3 infants aged 13 days, 8 weeks and 3 months who were exposed to NSC 272306NA in breastmilk.[2][3][4]

NSC 272306NA Possible Effects in Breastfeeding

NSC 272306NA can cause hyperprolactinemia and galactorrhea.[5][6] The clinical relevance of these findings in nursing mothers is not known. The maternal prolactin level in a mother with established lactation may not affect her ability to breastfeed.

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Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.