Is Ziv-Aflibercept Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Ziv-Aflibercept? Is Ziv-Aflibercept safe for nursing mother and child? Does Ziv-Aflibercept extracts into breast milk? Does Ziv-Aflibercept has any long term or short term side effects on infants? Can Ziv-Aflibercept influence milk supply or can Ziv-Aflibercept decrease milk supply in lactating mothers?

This record refers to the use of ziv-aflibercept for treating cancer. No information is available on the use of ziv-aflibercept during breastfeeding. Because ziv-aflibercept is a large protein molecule with a molecular weight of 115,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. However, ziv-aflibercept is usually used in combination with other potentially toxic chemotherapy agents and most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy. The manufacturer recommends avoiding breastfeeding during ziv-aflibercept therapy.