Question

I am a breastfeeding mother and i want to know if it is safe to use Cabozantinib? Is Cabozantinib safe for nursing mother and child? Does Cabozantinib extracts into breast milk? Does Cabozantinib has any long term or short term side effects on infants? Can Cabozantinib influence milk supply or can Cabozantinib decrease milk supply in lactating mothers?

Answer by DrLact: About Cabozantinib usage in lactation

No information is available on the clinical use of cabozantinib during breastfeeding. Because cabozantinib is more than 97% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life ranges from 55 to 99 hours and it might accumulate in the infant. The manufacturer recommends that breastfeeding be discontinued during cabozantinib therapy and for 4 months after the last dose.

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