Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-5Q7ZVV76EI? Is UNII-5Q7ZVV76EI safe for nursing mother and child? Does UNII-5Q7ZVV76EI extracts into breast milk? Does UNII-5Q7ZVV76EI has any long term or short term side effects on infants? Can UNII-5Q7ZVV76EI influence milk supply or can UNII-5Q7ZVV76EI decrease milk supply in lactating mothers?

UNII-5Q7ZVV76EI lactation summary

UNII-5Q7ZVV76EI is safe in breastfeeding
  • DrLact safety Score for UNII-5Q7ZVV76EI is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of UNII-5Q7ZVV76EI is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that UNII-5Q7ZVV76EI does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of UNII-5Q7ZVV76EI safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About UNII-5Q7ZVV76EI usage in lactation

Coumarin-type anticoagulant drug for the treatment and prophylaxis of thromboembolic disorders. UNII-5Q7ZVV76EI is not detected in breast milk. Not problems have been observed in infants whose mothers were treated. Plasma levels of UNII-5Q7ZVV76EI in such infants were undetectable. Even in cases of accidental maternal overdosing, infants did not show any clinical problem and/or coagulation tests were not altered. American Academy of Pediatrics states that it is a medication usually compatible with breastfeeding.WHO List of Essential Medicines 2002: compatible with breastfeeding.

Answer by DrLact: About UNII-5Q7ZVV76EI usage in lactation

Because of the very low milk levels with UNII-5Q7ZVV76EI doses up to at least 12 mg daily, amounts ingested by the infant are small. No adverse reactions in breastfed infants have been reported from maternal UNII-5Q7ZVV76EI use during lactation, even with a dose of 25 mg daily for 7 days. There is a consensus that maternal UNII-5Q7ZVV76EI therapy during breastfeeding poses little risk to the breastfed infant.[1][2][3][4][5] No special precautions are necessary.

UNII-5Q7ZVV76EI Side Effects in Breastfeeding

No decreases in vitamin K-dependent clotting factors or bleeding occurred in 2 infants who were breastfed for 56 and 131 days, respectively, during maternal anticoagulation with UNII-5Q7ZVV76EI.[6] In one telephone follow-up study, mothers taking UNII-5Q7ZVV76EI reported no adverse effects among 5 breastfed infants.[8] A mother had been taking UNII-5Q7ZVV76EI 5 mg daily for the first 7 weeks postpartum for a pulmonary embolism. At this time, she began taking 25 mg daily by mistake and took this dose for 7 days. Upon presentation to the emergency room, her INR was greater than 10 (usual therapeutic maximum 3.5), her prothrombin time was greater than 100 seconds (normal up to 11.2 seconds), and her aPTT was 62.5 seconds (normal up to 32.7 seconds). She had been nearly exclusively breastfeeding her infant since birth. Her 8-week-old infant was healthy with an INR of 1.0, prothrombin time of 10.3 seconds, and a slightly elevated aPTT 33.8 seconds. However, 3 weeks previously, the infant's aPTT was 38.9 seconds, so the elevated aPTT was judged not to be caused by UNII-5Q7ZVV76EI.[9]

Synonyms of UNII-5Q7ZVV76EI

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.