Is HSDB 7745 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use HSDB 7745? Is HSDB 7745 safe for nursing mother and child? Does HSDB 7745 extracts into breast milk? Does HSDB 7745 has any long term or short term side effects on infants? Can HSDB 7745 influence milk supply or can HSDB 7745 decrease milk supply in lactating mothers?

• DrLact safety Score for HSDB 7745 is 5 out of 8 which is considered Unsafe as per our analyses.
• A safety Score of 5 indicates that usage of HSDB 7745 may cause serious side effects in breastfed baby.
• Our study of different scientific research indicates that HSDB 7745 may cause moderate to high side effects or may affect milk supply in lactating mother.
• Our suggestion is to use safer alternate options rather than using HSDB 7745 .
• It is recommended to evaluate the advantage of not breastfeeding while using HSDB 7745 Vs not using HSDB 7745 And continue breastfeeding.
• While using HSDB 7745 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
• Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

No data on transfer into breastmilk are available. Indicated for treatment of schizophrenia. It may lengthen QT interval.

Because there is little published experience with HSDB 7745 during breastfeeding, other antipsychotic agents are preferred, especially while nursing a newborn or preterm infant.[1]

A woman took HSDB 7745 40 mg and citalopram 60 mg daily throughout pregnancy and postpartum. She breastfed extensively, except for occasional formula feedings by others. At 6 months of age, a pediatrician found the infant to be healthy with normal growth and development.[3]

Prolactin elevation has occurred during HSDB 7745 treatment,[4][5][6][7][8][9] and galactorrhea has been reported, often in adolescents.[4][5][6][7][10][11] However, prolactin elevation might be more transient and less severe than with phenothiazines.[12][13][14] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.