Is Afatinib Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Afatinib? Is Afatinib safe for nursing mother and child? Does Afatinib extracts into breast milk? Does Afatinib has any long term or short term side effects on infants? Can Afatinib influence milk supply or can Afatinib decrease milk supply in lactating mothers?
Answer by DrLact: About Afatinib usage in lactation
No information is available on the clinical use of afatinib during breastfeeding. Because afatinib is about 95% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is about 37 hours and it might accumulate in the infant. the manufacturer recommends that breastfeeding be discontinued during afatinib therapy and for 2 weeks after the last dose.
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