Question

I am a breastfeeding mother and i want to know if it is safe to use Ixazomib? Is Ixazomib safe for nursing mother and child? Does Ixazomib extracts into breast milk? Does Ixazomib has any long term or short term side effects on infants? Can Ixazomib influence milk supply or can Ixazomib decrease milk supply in lactating mothers?

Answer by DrLact: About Ixazomib usage in lactation

No information is available on the clinical use of ixazomib during breastfeeding. Because its half-life is about 9.5 days, it is likely to accumulate in the infant. It is also given in combination with leflunomide and dexamethasone, which may increase the risk to the infant. The manufacturer recommends that breastfeeding be discontinued during ixazomib therapy and for 90 days after the last dose.

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