Is Gefitinib Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Gefitinib? Is Gefitinib safe for nursing mother and child? Does Gefitinib extracts into breast milk? Does Gefitinib has any long term or short term side effects on infants? Can Gefitinib influence milk supply or can Gefitinib decrease milk supply in lactating mothers?
Answer by DrLact: About Gefitinib usage in lactation
No information is available on the clinical use of gefitinib during breastfeeding. Because gefitinib is 90% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is about 48 hours and it might accumulate in the infant. The manufacturer recommends that breastfeeding be discontinued during gefitinib therapy.
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