Is Ponatinib Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Ponatinib? Is Ponatinib safe for nursing mother and child? Does Ponatinib extracts into breast milk? Does Ponatinib has any long term or short term side effects on infants? Can Ponatinib influence milk supply or can Ponatinib decrease milk supply in lactating mothers?
Answer by DrLact: About Ponatinib usage in lactation
No information is available on the clinical use of ponatinib during breastfeeding. Because ponatinib is more than 99% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is about 24 hours and it might accumulate in the infant. The manufacturer recommends that breastfeeding be discontinued during ponatinib therapy and for 6 days following the last dose.
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