Is Betaxololum Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Betaxololum? Is Betaxololum safe for nursing mother and child? Does Betaxololum extracts into breast milk? Does Betaxololum has any long term or short term side effects on infants? Can Betaxololum influence milk supply or can Betaxololum decrease milk supply in lactating mothers?

Because of its relatively extensive excretion into breastmilk and minimal reported experience during breastfeeding, other beta-blocking agents may be preferred for systemic use, especially while nursing a newborn or preterm infant. With use of Betaxololum eye drops, it is not likely that sufficient amounts would be present in milk to affect the infant. To substantially diminish the amount of drug that reaches the breastmilk after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.

A study of mothers taking beta-blockers during nursing found a numerically, but not statistically significant increased number of adverse reactions in those taking any beta-blocker. Although the ages of infants were matched to control infants, the ages of the affected infants were not stated. None of the mothers were taking Betaxololum.[3] Beta-adrenergic blocking drugs with breastmilk excretion characteristics similar to Betaxololum have caused adverse effects in breastfed newborns.[4][5]

Relevant published information on the effects of beta-blockade or Betaxololum during normal lactation was not found as of the revision date. A study in 6 patients with hyperprolactinemia and galactorrhea found no changes in serum prolactin levels following beta-adrenergic blockade with propranolol.[6]