Is Palbociclib Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Palbociclib? Is Palbociclib safe for nursing mother and child? Does Palbociclib extracts into breast milk? Does Palbociclib has any long term or short term side effects on infants? Can Palbociclib influence milk supply or can Palbociclib decrease milk supply in lactating mothers?

No information is available on the clinical use of palbociclib during breastfeeding. Because palbociclib is 85% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is about 29 hours and it might accumulate in the infant. It is also given in combination with letrozole or fulvestrant, which may increase the risk to the infant. The manufacturer recommends that breastfeeding be discontinued during palbociclib therapy and for 3 weeks after the last dose.