Is (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol? Is (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol safe for nursing mother and child? Does (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol extracts into breast milk? Does (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol has any long term or short term side effects on infants? Can (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol influence milk supply or can (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol decrease milk supply in lactating mothers?
(RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol lactation summary
- DrLact safety Score for (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol usage in lactation
One case with no traces of this drug in the mother's milk has been reported. Until more information is available, safer options should be preferred.
Answer by DrLact: About (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol usage in lactation
Because there is little published experience with (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.
(RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol Side Effects in Breastfeeding
A study of mothers taking beta-blockers during nursing found a numerically, but not statistically significant increased number of adverse reactions in those taking any beta-blocker. Although the ages of infants were matched to control infants, the ages of the affected infants were not stated. None of the mothers were taking (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol.[3] Beta-adrenergic blocking drugs with similar breastmilk excretion characteristics have caused adverse effects in breastfed newborns.[4][5]
(RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol Possible Effects in Breastfeeding
A study in 6 patients with hyperprolactinemia and galactorrhea found no changes in serum prolactin levels following beta-adrenergic blockade with propranolol.[6] Relevant published information on the effects of beta-blockade or (RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol during normal lactation was not found as of the revision date.
Alternate Drugs
Nebivolol(Unsafe)
Nadolol(Unsafe)
Carvedilol(Low Risk)
Timolol(Safe)
Metoprolol(Safe)
Bisoprolol(Low Risk)
Sotalol(Low Risk)
Propranolol(Safe)
Atenolol(Unsafe)
Levobunolol(Low Risk)
Acebutolol(Unsafe)
Labetalol(Safe)
Carteolol(Unsafe)
Nadolol(Unsafe)
Amiodarone(Unsafe)
Lidocaine(Safe)
Timolol(Safe)
Mexiletine(Safe)
Metoprolol(Safe)
Disopyramide(Safe)
Bisoprolol(Low Risk)
Diltiazem(Safe)
Sotalol(Low Risk)
Digoxin(Safe)
Quinidine(Safe)
Propranolol(Safe)
Atenolol(Unsafe)
Levobunolol(Low Risk)
Propafenone(Low Risk)
Procainamide(Safe)
Acebutolol(Unsafe)
Labetalol(Safe)
Verapamil(Safe)
Flecainide(Safe)
Nifedipine(Safe)
Amlodipine(Low Risk)
Nicardipine(Safe)
Felodipine(Low Risk)
Trandolapril(Dangerous)
Minoxidil(Safe)
Nadolol(Unsafe)
Torsemide(Low Risk)
Enalapril(Safe)
Carvedilol(Low Risk)
Valsartan(Low Risk)
Terazosin(Unsafe)
Spironolactone(Safe)
Timolol(Safe)
Telmisartan(Unsafe)
Methyldopa(Safe)
Metoprolol(Safe)
Reserpine(Unsafe)
Diltiazem(Safe)
Bisoprolol(Low Risk)
Prazosin(Unsafe)
Ramipril(Low Risk)
Sotalol(Low Risk)
Losartan(Low Risk)
Lisinopril(Low Risk)
Chlorthalidone(Dangerous)
Irbesartan(Unsafe)
Isradipine(Low Risk)
Chlorothiazide(Safe)
Indapamide(Low Risk)
Propranolol(Safe)
Captopril(Safe)
Atenolol(Unsafe)
Eprosartan(Low Risk)
Levobunolol(Low Risk)
Bumetanide(Low Risk)
Doxazosin(Safe)
Hydrochlorothiazide(Safe)
Hydralazine(Safe)
Bosentan(Low Risk)
Nitrendipine(Safe)
Acebutolol(Unsafe)
Guanfacine(Low Risk)
Furosemide(Low Risk)
Nisoldipine(Low Risk)
Bendroflumethiazide(Unsafe)
Fosinopril(Low Risk)
Labetalol(Safe)
Nebivolol(Unsafe)
Nimodipine(Safe)
Benazepril(Safe)
Verapamil(Safe)